Microbiology Practice Exam

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What toxin is produced by Clostridium botulinum?

Endotoxin

Enterotoxin

Botulin toxin

Clostridium botulinum produces botulin toxin, which is one of the most potent neurotoxins known. This toxin specifically interferes with the release of acetylcholine at neuromuscular junctions, leading to paralysis. It is responsible for the severe illness known as botulism, which can occur from consuming improperly canned or preserved foods that contain the toxin.

In contrast to other types of toxins, botulin toxin is classified as an exotoxin because it is secreted by the bacteria into the environment. Endotoxin, typically associated with Gram-negative bacteria, is a component of the bacterial cell wall (lipopolysaccharide) and is not produced by C. botulinum. Enterotoxin, which often affects the intestines and is involved in gastrointestinal diseases, is also not related to Clostridium botulinum's pathogenic mechanism. Lipopolysaccharide, while significant in the context of Gram-negative bacterial infections, does not play a role in the action of Clostridium botulinum.

Understanding the specific nature of botulin toxin is crucial for recognizing its impact on human health and for implementing appropriate food safety measures to prevent botulism.

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Lipopolysaccharide

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